Diabetics at increased risk of COVID-19 death

One in seven patients with COVID-19 is diabetic, according to a foreigner of more than 78,000 hospitalized patients, said Dr. Nemencio Nicodemus, endocrinologist at the Philippine General Hospital.

Nicodemus, one of the guest speakers at the AstraZeneca Phils virtual data session. “Dapagliflozin New Indication”.

“People with pre-existing diabetes have been shown to have a twice-increased threat of developing severe COVID-19, and because of this, they also have an almost triple superior threat of dying in the hospital, due to COVID-19,” says Nicodemus.

He added that diabetic patients had a more serious diagnosis because they tended to have a more severe presentation and had a higher death threat because diabetes affects an individual’s immune system.

He said that when the blood sugar level is higher, the immune formula of the framework is weaker. Cells that are meant to protect the infection framework also react more slowly. Many diabetic patients also suffer from other comorities, such as upper blood pressure or central disease, which further complicate the framework’s ability to fight infections.

Worldwide, one in 11 adults now has diabetes and 80% of the burden is in low- and middle-income countries such as the Philippines, according to 2017 through the Diabetes Atlas of the International Diabetes Foundation. . Diabetes is responsible for 55% of deaths of adults under the age of 60 in the country.

Diabetes-related headaches, such as central ischemic disease, chronic kidney disease (CKD), and diabetes, are higher, particularly due to premature deaths in the Philippines. In the 10+ years, 2007 to In 2017, Nicodemus said, diabetes became the 11th leading cause. of death in the country to the seventh, the disease of the coronary center has of the eighth to the fifth, the disease of the ischemic center has of the third to the seventh place. First cause of premature death.

“Diabetes is a pandemic. This is a pandemic that even happened with COVID-19,” Nicodemus said.

The biggest tragedy here is that diabetes can be prevented, basically due to lifestyle and diet, which can be controlled through the patient.

CKD is a complication that worries doctors. Data from the Philippine Registry of Kidney Diseases show a slow increase in the number of Filipino dialysis patients.

“It should be stressed too much that nearly three-quarters of new dialysis patients are due to diseases that can be prevented primarily by following a healthy lifestyle, diet, exercise and quitting smoking,” dr. Elizabeth Roasa, nephrologist at the University of Santo Tomas. Hospital.

Roasa said that when diabetes is not controlled, “there is an inexorable decrease in kidneys that serve as over time. Medical science continues to seek new treatments to slow down, if not stop, the progression of CKD to the terminal stage. “

Four out of 10, or 41. 6%, for kidney failure due to diabetes.

“These chronic diseases not only shorten life, but are also very expensive. We want responses to morbidity, mortality and reducing costs,” said Dr. Subodh Verma, a scientific-cardiac surgeon in St. Louis. Michael from Toronto, Canada.

Dr. Erlyn Demerre, cardiologist at St. Louis Medical Center. Luke said the link between diabetes and the center failure was real, with nearly 70% of diabetics with a loss from the center that will serve in five years and that part of the center’s failure. “Heart failure is a forgotten first manifestation of type 2 diabetes headaches and is no more unusual than a central attack or stroke. “

Dapagliflozin (Forxiga), AstraZeneca’s diabetes drug, has been approved by the Philippine Food and Drug Administration to prevent the onset or worsening of central failure or cardiovascular death in adult patients with type 2 diabetes.

“There are more than 3. 7 million Filipinos with diabetes 2. Up to 50% of patients with diabetes 2 will expand the center’s insufficiency and up to 40% will expand chronic kidney disease. Half of the patients with center failure will die in five years,” Nicodemus said. -CONTRIBUTED

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